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Is 1000 mg of amoxicillin too much? The usual dose of amoxicillin is 250 mg to 500 mg three times a day or 750 mg to 1 g every 12 hours, depending on the severity and type of infection. Severe infections: 750 mg to 1 g three times a day. Do not take the next dose too soon, wait about 4 hours before taking the next dose.
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